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allithiamine
Sign in to saveAllithiamine (thiamine allyl disulfide or TAD) is a lipid-soluble form of vitamin B1 which was discovered in garlic (Allium sativum) in the 1950s along with its homolog prosultiamine. They were both investigated for their ability to treat Wernicke–Korsakoff syndrome and beriberi better than thiamine.
Chemical data
- Formula
- C15H22N4O2S2
- Molecular weight
- 354.5 g/mol
- IUPAC name
- N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-(prop-2-enyldisulfanyl)pent-2-en-2-yl]formamide
- SMILES
- CC1=NC=C(C(=N1)N)CN(C=O)/C(=C(/CCO)\SSCC=C)/C
- InChIKey
- WNCAVNGLACHSRZ-KAMYIIQDSA-N
- XLogP
- 0.9
- Polar surface area
- 143 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 354.118
Show 4 more facts
- chemical formula
- C₁₅H₂₂N₄O₂S₂
- canonical SMILES
- CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCO)SSCC=C)C
- isomeric SMILES
- CC1=NC=C(C(=N1)N)CN(C=O)/C(=C(/CCO)\SSCC=C)/C
- Commons category
- Allithiamine
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Allithiamine (thiamine allyl disulfide or TAD) is a lipid-soluble form of vitamin B1 which was discovered in garlic (Allium sativum) in the 1950s along with its homolog prosultiamine. They were both investigated for their ability to treat Wernicke–Korsakoff syndrome and beriberi better than thiamine.
== See also == Vitamin B1 analogue
Excerpted from Wikipedia’s “allithiamine” article, available under the CC BY-SA 4.0 licence.