metiamide

Also known as NSC 307755, SK&F 92058, Metiamida, Metiamidum, Methiamide

Metiamide is a histamine H2 receptor antagonist developed from another H2 antagonist, burimamide. It was an intermediate compound in the development of the successful anti-ulcer drug cimetidine (Tagamet).

Research

931 papers

Burimamide, metiamide, cimetidine..Lancet (London, England) · 1975
Histamine H2-receptor antagonists.Advances in internal medicine · 1978
Metiamide: an antagonist of histamine-stimulated gastric acid secretion.Annals of surgery · 1975
Metiamide: more than an H2-receptor antagonist.The American journal of digestive diseases · 1978
Histamine H2-receptor antagonists.Acta hepato-gastroenterologica · 1976

via PubMed

Wikidata facts

Mass: 244.082

Show 4 more facts

chemical formula: C₉H₁₆N₄S₂
isomeric SMILES: C/N=C(\S)/NCCSCC=1NC=NC1C
canonical SMILES: CC1=C(N=CN1)CSCCNC(=S)NC
Commons category: Metiamide

Sources (3)

via Wikidata · CC0

~3 min read

Article

4 sections

Contents

Development of metiamide from burimamide
Modification of metiamide to cimetidine
Synthesis
References

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| Section1 =