阿伏西地
Also known as flavopiridol, HL 275, HMR 1275, L 86-8275, L 868275, MDL-107826A, NSC-649890, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
化合物
Chemical data
- Formula
- C21H20ClNO5
- Molecular weight
- 401.8 g/mol
- IUPAC name
- 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- lymphoma, neoplasm, lymphoid neoplasm, multiple myeloma
via ChEMBL · EBI
Research
648 papers- Alvocidib (flavopiridol) for the treatment of chronic lymphocytic leukemia.Expert opinion on investigational drugs · 2016
- Clinical activity of alvocidib (flavopiridol) in acute myeloid leukemia.
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