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amedalin

Structure via PubChem · Public domain (PubChem)

EntityQ4742086· pop 6· linked from 897 articles

Amedalin (UK-3540-1) is an antidepressant which was synthesized in the early 1970s but was never marketed. It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.

Chemical data

Formula
C19H22N2O
Molecular weight
294.4 g/mol
IUPAC name
3-methyl-3-[3-(methylamino)propyl]-1-phenylindol-2-one
SMILES
CC1(C2=CC=CC=C2N(C1=O)C3=CC=CC=C3)CCCNC
InChIKey
HBGWAZBZXJBYQD-UHFFFAOYSA-N
XLogP
3.2
Polar surface area
32.3 Ų
H-bond donors
1
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
294.173
Show 3 more facts
chemical formula
C₁₉H₂₂N₂O
canonical SMILES
CC1(C2=CC=CC=C2N(C1=O)C3=CC=CC=C3)CCCNC
Commons category
Amedalin
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

Amedalin (UK-3540-1) is an antidepressant which was synthesized in the early 1970s but was never marketed. It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.

== See also == Daledalin

Excerpted from Wikipedia’s “amedalin” article, available under the CC BY-SA 4.0 licence.

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