Azatadine (Optimine) is a first-generation antihistamine and anticholinergic drug that was synthesized in 1963 by Schering-Plough, a former American pharmaceutical company. It is a nitrogen analog of cyproheptadine.
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Azatadine (Optimine) is a first-generation antihistamine and anticholinergic drug that was synthesized in 1963 by Schering-Plough, a former American pharmaceutical company. It is a nitrogen analog of cyproheptadine.
It was patented in 1967. It has been succeeded by both loratadine and desloratadine. and marketing approvals have been widely withdrawn. == Pharmacology == Azatadine exhibits potent antihistamine, anticholinergic, antiserotonin, and antianaphylactic properties. Its anticholinergic potency is one-third that of atropine and equivalent to that of promethazine and cyproheptadine. Azatadine is among the more potent antianaphylactic agents.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).