CEP120

Also known as CCDC100, SRTD13, centrosomal protein 120, JBTS31

Centrosomal protein of 120 kDa (Cep120), also known as coiled-coil domain-containing protein 100, is a protein that in humans is encoded by the CEP120 gene.

In the Vinony graph

Vinony's link graph records 33 inbound references to CEP120, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.

It sits within the topics Centrosome and Genes on human chromosome 5.

Vinony links it to 5 Wikipedia language editions.

Gene data

CEP120

Name: centrosomal protein 120
Type: protein-coding
Position: 123,344,888–123,423,592 (−)
Aliases: CCDC100, JBTS31, SRTD13
Ensembl: ENSG00000168944
RefSeq RNA: NM_001166226.2, NM_001375405.1, NM_001375406.1, NM_001375407.1, NM_001375408.1
RefSeq protein: NP_001159698.1, NP_001362334.1, NP_001362335.1, NP_001362336.1, NP_001362337.1

This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

Gene Ontology

Biological process

centrosome cycle centrosome cycle centrosome cycle regulation of centrosome duplication positive regulation of centrosome duplication positive regulation of centrosome duplication regulation of protein localization positive regulation of cilium assembly

Molecular function

protein binding

Cellular component

centrosome centrosome centrosome centriole centriole centriole

Pathways

via MyGene.info

Gene · Ensembl

centrosomal protein 120

Symbol: CEP120
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:123,344,888-123,423,592
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 27415
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/153241
genomic end: 122759286
genomic start: 122680579
chromosome: human chromosome 5
cytogenetic location: 5q23.2
genetic association: Joubert syndrome

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections

Contents

Function
References
External links
Further reading

Centrosomal protein of 120 kDa (Cep120), also known as coiled-coil domain-containing protein 100, is a protein that in humans is encoded by the CEP120 gene.

== Function ==

Excerpted from Wikipedia’s “CEP120” article, available under the CC BY-SA 4.0 licence.