کربوکسیلاستراز ۲
Sign in to saveAlso known as CE-2, CES2A1, PCE-2, iCE, Carboxylesterase 2, CES-2
protein-coding gene in the species Homo sapiens
Gene data
CES2- Name
- carboxylesterase 2
- Type
- protein-coding
- Position
- 66,934,433–66,945,096 (+)
- Aliases
- CE-2, CES2A1, PCE-2, iCE
- Ensembl
- ENSG00000172831
- RefSeq RNA
- NM_001365405.1, NM_001365406.1, NM_001365407.1, NM_001365408.1, NM_003869.6
- RefSeq protein
- NP_001352334.1, NP_001352335.1, NP_001352336.1, NP_001352337.1, NP_003860.3
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
carboxylesterase 2
- Symbol
- CES2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:66,934,433-66,945,096
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 128645
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8824
- genomic end
- 66978999
- genomic start
- 66968347
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.1
- expressed in
- kidney tubule
- Commons category
- Carboxylesterase 2
Sources (3)
via Wikidata · CC0