セビメリン
Sign in to saveAlso known as Cevimelina, 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Sni 2011, Cevimelinum, Evoxac
Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is used in the treatment of dry mouth and Sjögren's disease.
Research
231 papers- Cevimeline.2012
- Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration.International journal of molecular sciences · 2021
- Cevimeline.Drugs · 2008
- EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies.Annals of the rheumatic diseases · 2020
- Xerostomia of Various Etiologies: A Review of the Literature.Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2016
via PubMed
Article · 日本語
セビメリン（英:cevimeline）はアセチルコリン類似化合物の一つ。唾液腺に分布するムスカリン性アセチルコリン受容体に作用して、唾液分泌を促進する。主に口渇が症状として現れる疾患に、対症療法として用いられる。
Abstract from DBpedia / Wikipedia · CC BY-SA