Structure via PubChem · Public domain (PubChem)
Cevimelina
Sign in to saveAlso known as 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Sni 2011, Cevimelinum, Evoxac
compuesto químico
In the Vinony graph
Within Vinony's link graph, Cevimelina is referenced by 405 other articles, and connects out to atropine, muscarinic acetylcholine receptor family and International Standard Book Number.
It sits within the topics Daiichi Sankyo, Drugboxes which contain changes to verified fields and Drugboxes which contain changes to watched fields.
Its subject is documented across 17 Wikipedia language editions.
Chemical data
- Formula
- C10H17NOS
- Molecular weight
- 199.32 g/mol
- IUPAC name
- 2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane]
- SMILES
- CC1OC2(CN3CCC2CC3)CS1
- InChIKey
- WUTYZMFRCNBCHQ-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 37.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2000
- Admin. routes
- oral
- Indications
- xerostomia
via ChEMBL · EBI
Research
231 papers- Cevimeline.2012
- Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration.International journal of molecular sciences · 2021
- Cevimeline.Drugs · 2008
- EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies.Annals of the rheumatic diseases · 2020
- Xerostomia of Various Etiologies: A Review of the Literature.Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2016
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 199.103085
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₀H₁₇NOS
- subject has role
- muscarinic agonist
- canonical SMILES
- CC1OC2(CN3CCC2CC3)CS1
- defined daily dose
- 90
- medical condition treated
- Sjögren's syndrome
- Commons category
- Cevimeline
Sources (3)
via Wikidata · CC0
Connections
atropine
Entity
muscarinic acetylcholine receptor family
Entity
International Standard Book Number
Entity
headache
Entity
diarrhea
Entity
asthma
Entity
cough
Entity
sweat
Entity
vomiting
Entity
digital object identifier
Entity
chemical formula
Entity
insomnia
Disease
glaucoma
Entity
salivary gland
Entity
molar mass
Entity
nausea
Entity
PubMed
Entity
acetylcholine
Entity
CAS Registry Number
Entity
Mamba
Entity