CLCN6
Sign in to saveAlso known as CLC-6, chloride voltage-gated channel 6, CONRIBA
Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.
In the Vinony graph
Vinony's link graph records 300 inbound references to CLCN6, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
Vinony files it under Genes on human chromosome 1 and Ion channels.
Vinony links it to 5 Wikipedia language editions.
Gene data
CLCN6- Name
- Cl-/H+ antiporter 6
- Type
- protein-coding
- Position
- 11,806,096–11,848,080 (+)
- Aliases
- CLC-6, CONRIBA
- Ensembl
- ENSG00000011021
- RefSeq RNA
- NM_001256959.2, NM_001286.5, NM_021735.2, NM_021736.2, NM_021737.2
- RefSeq protein
- NP_001243888.2, NP_001277.2
This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
chloride voltage-gated channel 6
- Symbol
- CLCN6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:11,806,096-11,848,080
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 985
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1185
- chromosome
- human chromosome 1
- genomic start
- 11866207
- genomic end
- 11848079
- cytogenetic location
- 1p36.22
- expressed in
- anterior cingulate cortex
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.
Excerpted from Wikipedia’s “CLCN6” article, available under the CC BY-SA 4.0 licence.