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clofenciclan

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clofenciclan

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Clofenciclan (also known as chlorphencyclan; trade names Tonquil and Vesitan) is a dopamine-releasing agent developed by Boehringer & Soehne in the 1950s. It proved unpopular as a treatment because of its pronounced stimulant activity.

Chemical data

Formula
C18H28ClNO
Molecular weight
309.9 g/mol
IUPAC name
2-[1-(4-chlorophenyl)cyclohexyl]oxy-N,N-diethylethanamine
SMILES
CCN(CC)CCOC1(CCCCC1)C2=CC=C(C=C2)Cl
InChIKey
FFCARBNHUSWRGK-UHFFFAOYSA-N
XLogP
4.6
Polar surface area
12.5 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
309.186
Show 3 more facts
chemical formula
C₁₈H₂₈ClNO
canonical SMILES
CCN(CC)CCOC1(CCCCC1)C2=CC=C(C=C2)Cl
Commons category
Clofenciclan
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

Clofenciclan (also known as chlorphencyclan; trade names Tonquil and Vesitan) is a dopamine-releasing agent developed by Boehringer & Soehne in the 1950s. It proved unpopular as a treatment because of its pronounced stimulant activity.

Sila analogues of clorphencyclane were developed.

Excerpted from Wikipedia’s “clofenciclan” article, available under the CC BY-SA 4.0 licence.

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