Kortizol

Also known as 4-pregnen-11beta,17alpha,21-triol-3,20-dione, (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, HC, (1S,2R,10S,11S,14S,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, hydrocortisone, Kendall's compound F

Vücudun strese gösterdiği tepkiyle ilişkili bir kortikosteroid hormon

AI overview

Cortisol is a hormone your body naturally produces that helps regulate stress responses and other important functions. When doctors use it as a medicine, they call it hydrocortisone, and it can help treat various conditions related to inflammation and hormone imbalances.

AI-generated from the Wikipedia summary — may contain errors.

In the Vinony graph

Within Vinony's link graph, Kortizol is referenced by 1,410 other articles, and connects out to allergy, pituitary gland and epinephrine.

It sits within the topics Anxiety, Corticosteroids and ECHA InfoCard ID from Wikidata.

Its subject is documented across 65 Wikipedia language editions.

Chemical data

Formula: C21H30O5
Molecular weight: 362.5 g/mol
IUPAC name: (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O
InChIKey: JYGXADMDTFJGBT-VWUMJDOOSA-N
XLogP: 1.6
Polar surface area: 94.8 Å²
H-bond donors: 3
H-bond acceptors: 5
Formal charge: 0

via PubChem

Research

119,672 papers

Cortisol: Biosensing and detection strategies.ReviewClinica chimica acta; international journal of clinical chemistry · 2024Balasamy S, Atchudan R, Arya S et al.DOI: 10.1016/j.cca.2024.119888
Salivary cortisol and cortisone in the clinical setting.ReviewCurrent opinion in endocrinology, diabetes, and obesity · 2017Blair J, Adaway J, Keevil B et al.DOI: 10.1097/MED.0000000000000328
Cortisol Detection Methods and the Hormone's Role in Evaluating Circadian Rhythm Disruption.ReviewInternational journal of molecular sciences · 2025Juliana N, Maluin SM, Effendy NM et al.DOI: 10.3390/ijms26189141
Advancements in Cortisol Detection: From Conventional Methods to Next-Generation Technologies for Enhanced Hormone Monitoring.ReviewACS sensors · 2024Vignesh V, Castro-Dominguez B, James TD et al.DOI: 10.1021/acssensors.3c01912
Obesity and cortisol status.ReviewHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2005Salehi M, Ferenczi A, Zumoff BDOI: 10.1055/s-2005-861374
Early life stress and cortisol: A meta-analysis.ReviewHormones and behavior · 2018Fogelman N, Canli TDOI: 10.1016/j.yhbeh.2017.12.014
Measuring cortisol in human psychobiological studies.ReviewPhysiology & behavior · 2007Levine A, Zagoory-Sharon O, Feldman R et al.DOI: 10.1016/j.physbeh.2006.08.025
Cortisol metabolism, cortisol sensitivity and the pathogenesis of leprosy reactions.ReviewTropical medicine & international health : TM & IH · 1999Rook GA, Baker RDOI: 10.1046/j.1365-3156.1999.00432.x

via PubMed

Wikidata facts

Mass: 362.209

Show 9 more facts

chemical formula: C₂₁H₃₀O₅
melting point: 212.5
Commons category: Cortisol
canonical SMILES: CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
isomeric SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O
World Health Organisation international non-proprietary name: hydrocortisone
MCN code: 2937.21.20
stylized name: Solu-CORTEF
defined daily dose: 30