dimetindene

Chemical data

Formula

C20H24N2

Molecular weight

292.4 g/mol

IUPAC name

N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine

SMILES

CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C

InChIKey

MVMQESMQSYOVGV-UHFFFAOYSA-N

XLogP

2.7

Polar surface area

16.1 Ų

H-bond donors

0

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 3

Molecule type

Small molecule

Indications

Pruritus, allergic disease

via ChEMBL · EBI

• Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency.Cell · 2017
• Transdermal absorption of dimethindene in man.Archiv der Pharmazie · 1995
• Green Solvents for Eco-Friendly Synthesis of Dimethindene: A Forward-Looking Approach.Molecules (Basel, Switzerland) · 2022
• Structure-activity relationships of dimethindene derivatives as new M2-selective muscarinic receptor antagonists.Journal of medicinal chemistry · 2003
• Effect-kinetic characterization of dimethindene maleate following oral administration (Fenistil, Tropfen).Fundamental & clinical pharmacology · 1990

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

292.194

Has use

medication

via Wikidata · CC0