DIXDC1

Also known as CCD1, DIX domain containing 1

Dixin is a protein that in humans is encoded by the DIXDC1 gene. When active it stops cancer metastasis due to extreme stickiness, both in vitro and in vivo.

In the Vinony graph

Within Vinony's link graph, DIXDC1 is referenced by 3 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under topics including Genes associated with cancer and Genes on human chromosome 11.

Its subject is documented across 5 Wikipedia language editions.

Gene data

DIXDC1

Name: DIX domain containing 1
Type: protein-coding
Position: 111,927,144–112,023,091 (+)
Aliases: CCD1
Ensembl: ENSG00000150764
RefSeq RNA: NM_001037954.4, NM_001278542.2, NM_033425.5, XM_017018466.3, XM_017018467.2
RefSeq protein: NP_001033043.1, NP_001265471.1, NP_219493.1, XP_016873955.1, XP_016873956.1

The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013].

Gene Ontology

Biological process

Wnt signaling pathway cerebral cortex cell migration cerebral cortex radially oriented cell migration cell proliferation in forebrain forebrain ventricular zone progenitor cell division positive regulation of Wnt signaling pathway regulation of actin cytoskeleton organization negative regulation of neuron differentiation

Molecular function

protein binding protein domain specific binding gamma-tubulin binding

Cellular component

stress fiber cytoplasm cytoplasm cytosol cytosol cytosol focal adhesion postsynapse

via MyGene.info

Gene · Ensembl

DIX domain containing 1

Symbol: DIXDC1
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:111,927,144-112,023,091
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 82369
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/85458
chromosome: human chromosome 11
genomic start: 111797868
genomic end: 112022653
cytogenetic location: 11q23.1

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Dixin is a protein that in humans is encoded by the DIXDC1 gene. When active it stops cancer metastasis due to extreme stickiness, both in vitro and in vivo.

== References ==

Excerpted from Wikipedia’s “DIXDC1” article, available under the CC BY-SA 4.0 licence.