EML4
Sign in to saveAlso known as C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120, echinoderm microtubule associated protein like 4, EMAP like 4
Echinoderm microtubule-associated protein-like 4 is a protein that in humans is encoded by the EML4 gene.
Gene data
EML4- Name
- EMAP like 4
- Type
- protein-coding
- Aliases
- C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 56841
- exact match
- identifiers.org/ncbigene/27436
- genomic end
- 42559688
- genomic start
- 42169353
- cytogenetic location
- 2p21
Sources (3)
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Echinoderm microtubule-associated protein-like 4 is a protein that in humans is encoded by the EML4 gene.
This protein is involved in cancers when spliced with the anaplastic lymphoma kinase.