TUBA4A

Name

tubulin alpha 4a

Type

protein-coding

Position

219,249,710–219,277,902 (−)

Aliases

ALS22, CMYO26, FTDALS9, H2-ALPHA, OZEMA23, SPAX11, TUBA1

Ensembl

ENSG00000127824

RefSeq RNA

NM_001278552.2, NM_006000.3, XM_047445674.1, XM_054343669.1

RefSeq protein

NP_001265481.1, NP_005991.1, XP_047301630.1, XP_054199644.1

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013].

via MyGene.info

Gene · Ensembl

tubulin alpha 4a

Symbol

TUBA4A

Biotype

Protein coding

Organism

Homo sapiens

Location

2:219,249,710-219,277,902

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein TUBA4A PDB 1ffx.png

via Wikidata · CC0