F2RL2

Also known as PAR-3, PAR3, coagulation factor II thrombin receptor like 2

Protease activated receptor 3 (PAR-3) also known as coagulation factor II receptor-like 2 (F2RL2) and thrombin receptor-like 2, is a protein that in humans is encoded by the F2RL2 gene.

In the Vinony graph

Vinony's link graph records 486 inbound references to F2RL2, and connects out to PubMed, G protein-coupled recepteishon and Ensembl genome database project.

Vinony files it under Genes on human chromosome 5 and G protein-coupled receptors.

Vinony links it to 5 Wikipedia language editions.

Gene data

F2RL2

Name: coagulation factor II thrombin receptor like 2
Type: protein-coding
Position: 76,615,423–76,623,425 (−)
Aliases: PAR-3, PAR3
Ensembl: ENSG00000164220
RefSeq RNA: NM_001256566.2, NM_004101.4
RefSeq protein: NP_001243495.1, NP_004092.1

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012].

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)Complement and coagulation cascades - Homo sapiens (human)Hemostasis Hemostasis Signal Transduction Signaling by GPCR Class A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptors GPCR downstream signalling G alpha (q) signalling events

via MyGene.info

Gene · Ensembl

coagulation factor II thrombin receptor like 2

Symbol: F2RL2
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:76,615,423-76,623,425
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 36151
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/2151
genomic end: 76623413
genomic start: 75911307
chromosome: human chromosome 5
cytogenetic location: 5q13.3
expressed in: nipple

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

4 sections

Contents

Function
See also
References
Further reading

Protease activated receptor 3 (PAR-3) also known as coagulation factor II receptor-like 2 (F2RL2) and thrombin receptor-like 2, is a protein that in humans is encoded by the F2RL2 gene.

== Function ==

Excerpted from Wikipedia’s “F2RL2” article, available under the CC BY-SA 4.0 licence.