felbinac

Also known as p-biphenylylacetic acid, 4-carboxymethylbiphenyl, 4-biphenylylacetic acid, 4-biphenylacetic acid, Dolinac

Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis. It is an active metabolite of fenbufen.

In the Vinony graph

Vinony's link graph records 290 inbound references to felbinac, and connects out to salicylic acid, non-steroidal anti-inflammatory drug and metamizole sodium.

It is catalogued under topics including Drugboxes which contain changes to watched fields, ECHA InfoCard ID from Wikidata and Nonsteroidal anti-inflammatory drugs.

Vinony links it to 7 Wikipedia language editions.

Chemical data

Formula: C14H12O2
Molecular weight: 212.24 g/mol
IUPAC name: 2-(4-phenylphenyl)acetic acid
SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)CC(=O)O
InChIKey: QRZAKQDHEVVFRX-UHFFFAOYSA-N
XLogP: 3
Polar surface area: 37.3 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
Indications: Myalgia, Arthralgia, Acute kidney injury, pain

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 212.084

Show 4 more facts

chemical formula: C₁₄H₁₂O₂
canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)CC(=O)O
melting point: 161
Commons category: Felbinac

Sources (2)

via Wikidata · CC0

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Encyclopedic overview

3 sections

Contents

Related compounds
See also
References

==Related compounds== The α-methyl acid of felbinac is called biprofen and is used to prepare bifepramide. The α-ethyl acid is called xenbucin which is used to make xenthiorate.

Excerpted from Wikipedia’s “felbinac” article, available under the CC BY-SA 4.0 licence.