FGF17
Sign in to saveAlso known as FGF-13, HH20, FGF-17, fibroblast growth factor 17
Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene.
In the Vinony graph
Within Vinony's link graph, FGF17 is referenced by 369 other articles, and connects out to PubMed, human chromosome 8 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 8.
Its subject is documented across 5 Wikipedia language editions.
Gene data
FGF17- Name
- fibroblast growth factor 17
- Type
- protein-coding
- Position
- 22,042,388–22,048,809 (+)
- Aliases
- FGF-13, FGF-17, HH20
- Ensembl
- ENSG00000158815
- RefSeq RNA
- NM_001304478.1, NM_003867.4, XM_005273675.2, XM_011544683.2, XM_011544684.2
- RefSeq protein
- NP_001291407.1, NP_003858.1, XP_005273732.1, XP_011542985.1, XP_011542986.1
This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fibroblast growth factor 17
- Symbol
- FGF17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:22,042,388-22,048,809
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2872
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8822
- genomic end
- 21906320
- genomic start
- 21899909
- chromosome
- human chromosome 8
- cytogenetic location
- 8p21.3
- expressed in
- caudate nucleus
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development. This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.
Excerpted from Wikipedia’s “FGF17” article, available under the CC BY-SA 4.0 licence.