fondaparinux

Chemical data

Formula

C31H53N3O49S8

Molecular weight

1508.3 g/mol

IUPAC name

(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-2-carboxy-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-5-sulfooxyoxan-3-yl]oxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxy-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfoamino)-6-(sulfooxymethyl)oxan-2-yl]oxy-4,5-dihydroxyoxane-2-carboxylic acid

SMILES

CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COS(=O)(=O)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](O2)C(=O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COS(=O)(=O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COS(=O)(=O)O)O)O)NS(=O)(=O)O)O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O)NS(=O)(=O)O

InChIKey

KANJSNBRCNMZMV-ABRZTLGGSA-N

XLogP

-14.7

Polar surface area

873 Ų

H-bond donors

19

H-bond acceptors

52

Formal charge

0

via PubChem

• Fondaparinux Sodium: Recent Advances in the Management of Thrombosis.Journal of cardiovascular pharmacology and therapeutics · 2023
• Fondaparinux.Current pharmaceutical design · 2005
• Fondaparinux-associated heparin-induced thrombocytopenia.European journal of haematology · 2013
• Fondaparinux sodium.Drugs of today (Barcelona, Spain : 1998) · 2002
• Fondaparinux sodium.Drugs · 2002

via PubMed