ADGRG5
Sign in to saveAlso known as PGR27, GPR114, adhesion G protein-coupled receptor G5
G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
In the Vinony graph
Vinony's link graph records 484 inbound references to ADGRG5, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under topics including Genes on human chromosome 16 and G protein-coupled receptors.
Vinony links it to 5 Wikipedia language editions.
Gene data
ADGRG5- Name
- adhesion G protein-coupled receptor G5
- Type
- protein-coding
- Position
- 57,528,585–57,591,681 (+)
- Aliases
- GPR114, PGR27
- Ensembl
- ENSG00000159618
- RefSeq RNA
- NM_001304376.3, NM_001318481.2, NM_153837.4, XM_011522949.3, XM_011522950.3
- RefSeq protein
- NP_001291305.1, NP_001305410.1, NP_722579.1, XP_011521251.2, XP_011521252.1
This gene encodes a member of the adhesion family of G-protein coupled receptors. Members of this family are characterized by long N-termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor G5
- Symbol
- ADGRG5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:57,528,585-57,591,681
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 17828
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/221188
- genomic end
- 57625593
- genomic start
- 57542643
- chromosome
- human chromosome 16
- cytogenetic location
- 16q21
- expressed in
- tonsil
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Tissue distribution
- Signaling
- References
- External links
G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
== Tissue distribution ==
Excerpted from Wikipedia’s “ADGRG5” article, available under the CC BY-SA 4.0 licence.