Structure via PubChem · Public domain (PubChem)
گلیکوئیدون
Sign in to saveAlso known as ARDF-26, Glurenorm, Gliquidone
Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic medication in the sulfonylurea class. It is classified as a second-generation sulfonylurea. It is used in the treatment of diabetes mellitus type 2. It is marketed by the pharmaceutical company Boehringer Ingelheim (Germany).
Chemical data
- Formula
- C27H33N3O6S
- Molecular weight
- 527.6 g/mol
- IUPAC name
- 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- diabetes mellitus
via ChEMBL · EBI
Research
187 papers- Gliquidone.Acta crystallographica. Section E, Structure reports online · 2011
- Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1(-/-) rats.European journal of pharmacology · 2021
- Gliquidone contributes to improvement of type 2 diabetes mellitus management: a review of pharmacokinetic and clinical trial data.Drugs in R&D · 2006
- Gliquidone Alleviates Diabetic Nephropathy by Inhibiting Notch/Snail Signaling Pathway.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2018
- Inhibition of Cardiac Kv4.3/KChIP2 Channels by Sulfonylurea Drug Gliquidone.Molecular pharmacology · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 527.209
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₇H₃₃N₃O₆S
- World Health Organisation international non-proprietary name
- gliquidone
- canonical SMILES
- CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C
- defined daily dose
- 60
- subject has role
- anti-diabetic medication
Sources (3)
via Wikidata · CC0
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via Wikidata sitelinks · CC0