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Homoharringtonin · Vinony

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Alkaloids
Homoharringtonin

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EntityQ7089373· pop 13· linked from 280 articles

Homoharringtonin

Also known as CGX-635, omacetaxine mepesuccinate, Cephalotaxus alkaloid, HHT, Myelostat

chemische Verbindung

Research

842 papers

Homoharringtonine inhibits the NOTCH/MYC pathway and exhibits antitumor effects in T-cell acute lymphoblastic leukemia.Blood · 2024
Homoharringtonine in the treatment of acute myeloid leukemia: A review.Medicine · 2024
Venetoclax Combined with Azacitidine and Homoharringtonine in Relapsed/Refractory AML: A Multicenter, Phase 2 Trial.Journal of hematology & oncology · 2023
Homoharringtonine: updated insights into its efficacy in hematological malignancies, diverse cancers and other biomedical applications.European journal of medical research · 2024
Homoharringtonine synergizes with venetoclax in early T cell progenitor acute lymphoblastic leukemia: Bench and bed.Med (New York, N.Y.) · 2024

Wikidata facts

Mass: 545.262482

Article · Deutsch

Homoharringtonin ist ein Alkaloid aus der Gruppe der Cephalotaxus-Alkaloide.

Abstract from DBpedia / Wikipedia · CC BY-SA

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Connections

chronic myeloid leukemia

Categories

Alkaloids Benzazepanes Chemical pages without DrugBank identifier Cyclopentenes ECHA InfoCard ID from Wikidata Enol ethers Esters Heterocyclic compounds with 5 rings Methoxy compounds Methylenedioxyphenethylamines Methyl esters Orphan drugs Tertiary alcohols

Sources

wikipedia.externallinksexternallink

Show 5 more facts

chemical formula: C₂₉H₃₉NO₉
isomeric SMILES: COC(=O)C[C@](O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@H]2C3=CC4=C(OCO4)C=C3CCN5CCC[C@]25C=C1OC
canonical SMILES: CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O
NCI Thesaurus ID: C1127
Commons category: Omacetaxine mepesuccinate

Sources (3)

wikidata.org
commonchemistry.cas.org
docs.openalex.org

via Wikidata · CC0

via Wikidata sitelinks · CC0

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