File:Allergy_to_Antibiotic_Cefaclor.JPG · Wikimedia Commons · See Wikimedia Commons

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Also known as hyperchemokinemia, inflammatory reaction

Inflammation (from ) is part of the biological defence response of body tissues. Inflammatory immunovascular responses can be triggered by a broad range of stimuli, including physical trauma, "dead, damaged, malfunctioning or stressed tissues", pathogens, irritants, toxins, overuse, autoimmunity, allergens, and foreign bodies (e.g. silica and asbestos). The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa).

AI overview

Inflammation is your body's natural defense response when tissues are damaged or threatened by things like injuries, infections, toxins, or allergens. You typically notice it through five main signs: heat, pain, redness, swelling, and loss of function in the affected area.

AI-generated from the Wikipedia summary — may contain errors.

Key facts

Medical condition.caption: An allergic reaction to cefaclor has led to inflammation of the skin on the foot. The cardinal signs of inflammation include: pain, heat, redness, swelling, and loss of function. Some of these indicators can be seen here.
Medical condition.specialty: Immunology, rheumatology
Medical condition.symptoms: Heat, pain, redness, swelling
Medical condition.complications: Asthma, pneumonia, autoimmune diseases
Medical condition.duration: Acute: few daysChronic: up to many months, or years
Medical condition.causes: Infection, physical injury, autoimmune disorder
Medical condition.image: Allergy to Antibiotic Cefaclor.JPG

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Research

1,136,246 papers

Inflammation in multiple system atrophy.ReviewFrontiers in immunology · 2023Leńska-Mieciek M, Madetko-Alster N, Alster P et al.DOI: 10.3389/fimmu.2023.1214677
Role of Antioxidants and Natural Products in Inflammation.ReviewOxidative medicine and cellular longevity · 2016Arulselvan P, Fard MT, Tan WS et al.DOI: 10.1155/2016/5276130
Chronic Inflammation's Transformation to Cancer: A Nanotherapeutic Paradigm.ReviewMolecules (Basel, Switzerland) · 2023Sohrab SS, Raj R, Nagar A et al.DOI: 10.3390/molecules28114413
Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond.ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Michopoulos V, Powers A, Gillespie CF et al.DOI: 10.1038/npp.2016.146
Stimulus-Responsive Hydrogels as Drug Delivery Systems for Inflammation Targeted Therapy.ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Yu H, Gao R, Liu Y et al.DOI: 10.1002/advs.202306152
Inflammation and atherosclerotic cardiovascular disease: where do we go from here?ReviewCurrent opinion in lipidology · 2025Waksman O, Waksman RDOI: 10.1097/MOL.0000000000001009
Inflammation preservation strategy: reconciling pain control and disc resorption in lumbar disc herniation.ReviewFrontiers in immunology · 2025Gong G, Yan Z, Lai Q et al.DOI: 10.3389/fimmu.2025.1653681
Inflammation and immune biomarkers: new frontiers in understanding and managing diabetes complications.ReviewInflammopharmacology · 2025Rao PP, Mishra S, Gupta J et al.DOI: 10.1007/s10787-025-01996-4

Wikidata facts

Image: Acute inflammatory exudate.jpg

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Commons category: Inflammations
topic's main category: Category:Inflammatory diseases of the central nervous system
Commons gallery: Inflammation
on focus list of Wikimedia project: Wikipedia:Vital articles/Level/4
topic has template: Template:Inflammation
manifestation of: innate immune response
exact match: purl.obolibrary.org/obo/SYMP_0000061
WordLift URL: data.wordlift.io/wl01714/entity/inflammation.html

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