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isoflurane

Structure via PubChem · Public domain (PubChem)

EntityQ413918· pop 36· linked from 2,721 articles

isoflurane

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Also known as Compound 469, Forane, Aerrane, 1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether, Forene, Isoflurano, Isofluranum

Isoflurane, sold under the brand name Forane among others, is a halogenated ether used as a general anesthetic. It can be used to start or maintain anesthesia; however, other medications are often used to start anesthesia, due to airway irritation with isoflurane. Isoflurane is a inhalational anesthetic given via inhalation.

Key facts

Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
443883276
Drug.image
Isoflurane.svg
Drug.image_class
skin-invert-image
Drug.width
150
Drug.image2
Isoflurane-3D-vdW.png
Drug.image_class2
bg-transparent
Drug.width2
150
Drug.tradename
Forane, others
Drug.DailyMedID
Isoflurane
Drug.pregnancy_AU
B3
Drug.routes_of_administration
Respiratory
Drug.class
Inhalational anesthetic
Drug.ATC_prefix
N01
Drug.ATC_suffix
AB06
Drug.legal_BR
C1
Drug.legal_UK
POM

via Wikipedia infobox

Chemical data

Formula
C3H2ClF5O
Molecular weight
184.49 g/mol
IUPAC name
2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
SMILES
C(C(F)(F)F)(OC(F)F)Cl
InChIKey
PIWKPBJCKXDKJR-UHFFFAOYSA-N
XLogP
2.1
Polar surface area
9.2 Ų
H-bond donors
0
H-bond acceptors
6
Formal charge
0

via PubChem

Wikidata facts

Mass
183.971
Show 5 more facts
Commons category
Isoflurane
chemical formula
C₃H₂ClF₅O
canonical SMILES
C(C(F)(F)F)(OC(F)F)Cl
World Health Organisation international non-proprietary name
isoflurane
global warming potential
595
Sources (4)

via Wikidata · CC0

~5 min read

Article

10 sections
Contents
  • Medical uses
  • Mechanism of action
  • Adverse effects
  • Elderly
  • Anesthetic physical properties
  • History
  • Environment
  • Veterinary use
  • References
  • External links

Isoflurane, sold under the brand name Forane among others, is a halogenated ether used as a general anesthetic. It can be used to start or maintain anesthesia; however, other medications are often used to start anesthesia, due to airway irritation with isoflurane. Isoflurane is a inhalational anesthetic given via inhalation.

Isoflurane was approved for medical use in the United States in 1979. It is on the World Health Organization's List of Essential Medicines.

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