KIF21A
Sign in to saveAlso known as CFEOM1, FEOM1, FEOM3A, kinesin family member 21A
Kinesin-like protein KIF21A is a protein that in humans is encoded by the KIF21A gene.
Gene data
KIF21A- Name
- kinesin family member 21A
- Type
- protein-coding
- Position
- 39,293,228–39,443,718 (−)
- Aliases
- CFEOM1, FEOM1, FEOM3A
- Ensembl
- ENSG00000139116
- RefSeq RNA
- NM_001173463.2, NM_001173464.2, NM_001173465.2, NM_001378439.1, NM_001378440.1
- RefSeq protein
- NP_001166934.1, NP_001166935.1, NP_001166936.1, NP_001365368.1, NP_001365369.1
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
kinesin family member 21A
- Symbol
- KIF21A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:39,293,228-39,443,718
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 56761
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55605
- genomic end
- 39837192
- genomic start
- 39687030
- chromosome
- human chromosome 12
- cytogenetic location
- 12q12
- expressed in
- ventral tegmental area
via Wikidata · CC0
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Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Kinesin-like protein KIF21A is a protein that in humans is encoded by the KIF21A gene.
KIF21A belongs to a family of plus end-directed kinesin motor proteins. Neurons use kinesin and dynein microtubule-dependent motor proteins to transport essential cellular components along axonal and dendritic microtubules.
Excerpted from Wikipedia’s “KIF21A” article, available under the CC BY-SA 4.0 licence.