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EntityQ6543740· pop 5· linked from 471 articles

lidoflazine

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Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action. Lidoflazine was discovered at Janssen Pharmaceutica in 1964. In 2025 Lidoflazine has also been reported to interact with tubulin and inhibit its polymerization.

Wikidata facts

Mass
491.275
Show 3 more facts
chemical formula
C₃₀H₃₅F₂N₃O
canonical SMILES
CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
subject has role
calcium channel blocker
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

4 sections
Contents
  • Physical properties
  • Solubility at room temperature
  • References
  • Further reading

Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action. Lidoflazine was discovered at Janssen Pharmaceutica in 1964. In 2025 Lidoflazine has also been reported to interact with tubulin and inhibit its polymerization.

==Physical properties== ===Solubility at room temperature===

Excerpted from Wikipedia’s “lidoflazine” article, available under the CC BY-SA 4.0 licence.

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