Structure via PubChem · Public domain (PubChem)
mebeverine
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Mebeverine is a drug used to alleviate some of the symptoms of irritable bowel syndrome. It works by relaxing the muscles in and around the gut.
Chemical data
- Formula
- C25H35NO5
- Molecular weight
- 429.5 g/mol
- IUPAC name
- 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl 3,4-dimethoxybenzoate
- SMILES
- CCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC
- InChIKey
- VYVKHNNGDFVQGA-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 57.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
233 papers- The Efficacy of Mebeverine in the Treatment of Irritable Bowel Syndrome-A Systematic Review.Journal of clinical medicine · 2022
- Mebeverine and the Influence of Labeling in Adolescents With Irritable Bowel Syndrome or Functional Abdominal Pain Not Otherwise Specified: A 2 × 2 Randomized, Placebo-Controlled Trial.Gastroenterology · 2025
- Clinical efficacy of mebeverine for persistent nocturnal enuresis after orthotopic W-neobladder.BJU international · 2022
- A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome.World journal of gastroenterology · 2010
- [Development of selective method for identifying mebeverine in hair].Sudebno-meditsinskaia ekspertiza · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 429.252
- Has use
- medication
Show 4 more facts
- Commons category
- Mebeverine
- chemical formula
- C₂₅H₃₅NO₅
- canonical SMILES
- CCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC
- subject has role
- parasympatholytic
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
8 sectionsContents
- Medical use
- Adverse effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- History
- Availability
- References
Mebeverine is a drug used to alleviate some of the symptoms of irritable bowel syndrome. It works by relaxing the muscles in and around the gut.
==Medical use== Mebeverine is used to alleviate some of the symptoms of irritable bowel syndrome (IBS) and related conditions; specifically stomach pain and cramps, persistent diarrhoea, and flatulence.
Excerpted from Wikipedia’s “mebeverine” article, available under the CC BY-SA 4.0 licence.