Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Vinony's link graph records 460 inbound references to mebeverina, and connects out to 2C-G, D-methamphetamine and atropine.
Vinony files it under 4-Methoxyphenyl compounds, Amines and Benzoate esters.
Vinony links it to 23 Wikipedia language editions.
Chemical data
- Formula
- C25H35NO5
- Molecular weight
- 429.5 g/mol
- IUPAC name
- 4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butyl 3,4-dimethoxybenzoate
- SMILES
- CCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC
- InChIKey
- VYVKHNNGDFVQGA-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 57.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- irritable bowel syndrome, gastrointestinal disease
via ChEMBL · EBI
Research
233 papers- The Efficacy of Mebeverine in the Treatment of Irritable Bowel Syndrome-A Systematic Review.Journal of clinical medicine · 2022
- Mebeverine and the Influence of Labeling in Adolescents With Irritable Bowel Syndrome or Functional Abdominal Pain Not Otherwise Specified: A 2 × 2 Randomized, Placebo-Controlled Trial.Gastroenterology · 2025
- Clinical efficacy of mebeverine for persistent nocturnal enuresis after orthotopic W-neobladder.BJU international · 2022
- A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome.World journal of gastroenterology · 2010
- [Development of selective method for identifying mebeverine in hair].Sudebno-meditsinskaia ekspertiza · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 429.252
- Has use
- medication
Show 4 more facts
- Commons category
- Mebeverine
- chemical formula
- C₂₅H₃₅NO₅
- canonical SMILES
- CCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC
- subject has role
- parasympatholytic
Sources (2)
via Wikidata · CC0
Article · Italiano
La mebeverina è un antispastico utilizzato nella sindrome del colon irritabile (IBS). A differenza di altri farmaci d'uso comune, la mebeverina non ha un'azione anticolinergica. Gli studi dimostrano che la sua azione si esplica direttamente sulle fibre muscolari lisce, riducendo la permeabilità al sodio e al calcio in modo tale da ridurne la contrazione. Viene somministrato come mebeverina cloridrato con numero CAS 2753-45-9.
Abstract from DBpedia / Wikipedia · CC BY-SA