-Midodrin%20Structural%20Formula%20V1.svg)
midodrine
Sign in to saveMidodrine, sold under the brand name Proamatine among others, is an antihypotensive medication used to treat orthostatic hypotension (low blood pressure when standing) and urinary incontinence. It is taken by mouth.
Key facts
- Drug.KEGG
- D08220
- Drug.ChEBI
- 6933
- Drug.ChEMBL
- 1201212
- Drug.image
- Midodrine structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250px
- Drug.caption
- Above: molecular structure of midodrineBelow: 3D representation of midodrine
- Drug.image2
- Midodrine 3D.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250px
- Drug.tradename
- Proamatine, others
- Drug.MedlinePlus
- a616030
- Drug.DailyMedID
- Midodrine
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth
- Drug.class
- α1-Adrenergic receptor agonist; Antihypotensive agent
- Drug.ATC_prefix
- C01
- Drug.ATC_suffix
- CA17
via Wikipedia infobox
Article
16 sectionsContents
- Medical uses
- Available forms
- Contraindications
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Stereochemistry
- Synthesis
- History
- Society and culture
- Names
- See also
- References
- External links
Midodrine, sold under the brand name Proamatine among others, is an antihypotensive medication used to treat orthostatic hypotension (low blood pressure when standing) and urinary incontinence. It is taken by mouth.
Side effects of midodrine include hypertension (high blood pressure), paresthesia, itching (pruritus), goose bumps, chills, urinary urgency, urinary retention, and urinary frequency. Midodrine is a prodrug of its active metabolite desglymidodrine. This metabolite acts as a selective agonist of the α1-adrenergic receptor. This in turn results in vasoconstriction and increased blood pressure.