Structure via PubChem · Public domain (PubChem)
میتیگلینید
Sign in to saveAlso known as Mitiglinide calcium hydrate, KAD-1229, Mitiglinide
Mitiglinide (INN, trade name Glufast) is a drug for the treatment of type 2 diabetes.
Chemical data
- Formula
- C19H25NO3
- Molecular weight
- 315.4 g/mol
- IUPAC name
- (2S)-4-[(3aR,7aS)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-2-benzyl-4-oxobutanoic acid
- SMILES
- C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)O
- InChIKey
- WPGGHFDDFPHPOB-BBWFWOEESA-N
- XLogP
- 3
- Polar surface area
- 57.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- diabetes mellitus, type 2 diabetes mellitus
via ChEMBL · EBI
Research
163 papers- Mitiglinide: a novel agent for the treatment of type 2 diabetes mellitus.The Annals of pharmacotherapy · 2010
- Mitiglinide for type 2 diabetes treatment.Expert opinion on pharmacotherapy · 2013
- Mitiglinide: KAD 1229, S 21403.Drugs in R&D · 2004
- Mitiglinide: a rapid- and short-acting non-sulfonylurea insulinotropic agent for the treatment of type 2 diabetic patients.Expert opinion on pharmacotherapy · 2008
- [Mitiglinide (KAD-1229)].Nihon rinsho. Japanese journal of clinical medicine · 2002
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 315.183444
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₉H₂₅NO₃
- isomeric SMILES
- C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)O
- canonical SMILES
- C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)O
- defined daily dose
- 30
- subject has role
- anti-diabetic medication
via Wikidata · CC0