mizolastine

Mizolastine (Tradename: Mizollen) is a once-daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting. It does not prevent the actual release of histamine from mast cells, it only prevents histamine from binding to receptors. Side effects can include dry mouth and throat.

Key facts

Drug.ChemSpiderID: 59315
Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 449584902
Drug.IUPAC_name: 2-[{1-[1-(4-Fluorobenzyl)-1H-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(1H)-one
Drug.image: Mizolastine.svg
Drug.image_class: skin-invert-image
Drug.tradename: Mizollen
Drug.legal_UK: POM
Drug.routes_of_administration: By mouth (tablets)
Drug.CAS_number: 108612-45-9
Drug.ATC_prefix: R06
Drug.ATC_suffix: AX25
Drug.PubChem: 65906
Drug.UNII: 244O1F90NA
Drug.KEGG: D01117
Drug.ChEMBL: 94454
Drug.C: 24

via Wikipedia infobox

Research

131 papers

Clinical pharmacokinetics of mizolastine.Clinical pharmacokinetics · 2001
Mizolastine: antihistaminic activity from preclinical data to clinical evaluation.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 1999
Second-generation antihistamines: a comparative review.Drugs · 1999
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.Fundamental & clinical pharmacology · 2004
Mizolastine in primary acquired cold urticaria.Journal of the American Academy of Dermatology · 2003

via PubMed

~2 min read

Encyclopedic overview

1 sections

Contents

References

{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449584902 | IUPAC_name = 2-[{1-[1-(4-Fluorobenzyl)-1H-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(1H)-one | image = Mizolastine.svg | image_class = skin-invert-image

Excerpted from Wikipedia’s “mizolastine” article, available under the CC BY-SA 4.0 licence.

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