Structure via PubChem · Public domain (PubChem)
osthol
Sign in to saveAlso known as Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-, 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-
Osthol, or osthole, is a chemical compound which is a derivative of coumarin. It is found in a variety of plants including Cnidium monnieri, Angelica archangelica and Angelica pubescens.
Chemical data
- Formula
- C15H16O3
- Molecular weight
- 244.28 g/mol
- IUPAC name
- 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one
- SMILES
- CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
- InChIKey
- MBRLOUHOWLUMFF-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 35.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
829 papers- Potential Anticancer Properties of Osthol: A Comprehensive Mechanistic Review.Nutrients · 2018
- Osthol Ameliorates Kidney Damage and Metabolic Syndrome Induced by a High-Fat/High-Sugar Diet.International journal of molecular sciences · 2021
- Design, Preparation, and Evaluation of Osthol Poly-Butyl-Cyanoacrylate Nanoparticles with Improved In Vitro Anticancer Activity in Neuroblastoma Treatment.Molecules (Basel, Switzerland) · 2022
- Osthol attenuates hepatic steatosis via decreased triglyceride synthesis not by insulin resistance.World journal of gastroenterology · 2014
- Synthesis, characterization, and antimicrobial evaluation of polyvinylalcohol-osthol composite films.Turkish journal of chemistry · 2022
via PubMed
Wikidata facts
- Mass
- 244.11
Show 3 more facts
- chemical formula
- C₁₅H₁₆O₃
- canonical SMILES
- CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
- subject has role
- calcium channel blocker
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Osthol, or osthole, is a chemical compound which is a derivative of coumarin. It is found in a variety of plants including Cnidium monnieri, Angelica archangelica and Angelica pubescens.
== References ==
Excerpted from Wikipedia’s “osthol” article, available under the CC BY-SA 4.0 licence.