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periciazine

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EntityQ2622907· pop 12· linked from 617 articles

periciazine

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Also known as pericyazine, propericiazine, RP-8909, Piperocyanomazine, 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine, 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine, 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile

Periciazine (INN), also known as pericyazine (BAN) or propericiazine, is a drug that belongs to the phenothiazine class of typical antipsychotics.

Chemical data

Formula
C21H23N3OS
Molecular weight
365.5 g/mol
IUPAC name
10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile
SMILES
C1CN(CCC1O)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C#N
InChIKey
LUALIOATIOESLM-UHFFFAOYSA-N
XLogP
3.5
Polar surface area
75.8 Ų
H-bond donors
1
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
Indications
psychosis

via ChEMBL · EBI

Wikidata facts

Has part
carbon
Mass
365.156183
Has use
medication
Show 6 more facts
Commons category
Periciazine
significant drug interaction
lithium
chemical formula
C₂₁H₂₃N₃OS
canonical SMILES
C1CN(CCC1O)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C#N
World Health Organisation international non-proprietary name
periciazine
defined daily dose
20
Sources (3)

via Wikidata · CC0

~4 min read

Encyclopedic overview

4 sections
Contents
  • Medical uses
  • Adverse effects
  • References
  • External links

Periciazine (INN), also known as pericyazine (BAN) or propericiazine, is a drug that belongs to the phenothiazine class of typical antipsychotics.

Periciazine is not approved for sale in the United States. It is commonly sold in Canada, Italy and Russia under the tradename Neuleptil and in United Kingdom and Australia under the tradename Neulactil.

Excerpted from Wikipedia’s “periciazine” article, available under the CC BY-SA 4.0 licence.