سابکوملین

Also known as SB-202026

Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease. It made it to phase III clinical trials before being discontinued due to poor results.

Chemical data

Formula: C10H15N3O
Molecular weight: 193.25 g/mol
IUPAC name: (3Z,3R)-N-methoxy-1-azabicyclo[2.2.2]octane-3-carboximidoyl cyanide
SMILES: CO/N=C(\C#N)/[C@H]1CN2CCC1CC2
InChIKey: IQWCBYSUUOFOMF-QTLFRQQHSA-N
XLogP: 1
Polar surface area: 48.6 Å²
H-bond donors: 0
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 193.121512

Show 4 more facts

chemical formula: C₁₀H₁₅N₃O
isomeric SMILES: CO/N=C(\C#N)/[C@H]1CN2CCC1CC2
canonical SMILES: CON=C(C#N)C1CN2CCC1CC2
Commons category: Sabcomeline

Sources (3)

via Wikidata · CC0

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via Wikidata sitelinks · CC0