Structure via PubChem · Public domain (PubChem)
solabegron
Sign in to saveAlso known as GW-427,353
Solabegron (code name GW-427,353) is a drug which acts as a selective agonist for the β3 adrenergic receptor. It is being developed for the treatment of overactive bladder and irritable bowel syndrome. It has been shown to produce visceral analgesia by releasing somatostatin from adipocytes.
Chemical data
- Formula
- C23H24Cl2N2O3
- Molecular weight
- 447.4 g/mol
- IUPAC name
- 3-[3-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethylamino]phenyl]benzoic acid;hydrochloride
- SMILES
- C1=CC(=CC(=C1)C(=O)O)C2=CC(=CC=C2)NCCNCC(C3=CC(=CC=C3)Cl)O.Cl
- InChIKey
- PMXCGBVBIRYFPR-UHFFFAOYSA-N
- Polar surface area
- 81.6 Ų
- H-bond donors
- 5
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 446.116398
Show 3 more facts
- chemical formula
- C₂₃H₂₄Cl₂N₂O₃
- canonical SMILES
- C1=CC(=CC(=C1)C(=O)O)C2=CC(=CC=C2)NCCNCC(C3=CC(=CC=C3)Cl)O.Cl
- Commons category
- Solabegron
Sources (1)
via Wikidata · CC0
~3 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 448116125 | IUPAC_name = 3'-[(2-{[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino}ethyl)amino]-3-biphenylcarboxylic acid | image = Solabegron.svg | image_class = skin-invert-image | width = 300
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “solabegron” article, available under the CC BY-SA 4.0 licence.