sparsentan
Sign in to saveAlso known as BMS-346567, compound 7 [PMID 15634011], RE-021, retrophin, DARA-a (Dual Acting Receptor Antagonist of angiotension and endothelin receptors)
Sparsentan, sold under the brand name Filspari, is a medication used for the treatment of primary immunoglobulin A nephropathy. Sparsentan is an endothelin and angiotensin II receptor antagonist. It is taken by mouth.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 592.271941
Show 3 more facts
- chemical formula
- C₃₂H₄₀N₄O₅S
- canonical SMILES
- CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC
- legal status (medicine)
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Encyclopedic overview
7 sectionsContents
- Medical uses
- Adverse effects
- History
- Society and culture
- Legal status
- References
- External links
Sparsentan, sold under the brand name Filspari, is a medication used for the treatment of primary immunoglobulin A nephropathy. Sparsentan is an endothelin and angiotensin II receptor antagonist. It is taken by mouth.
The most common side effects include swelling of the extremities, low blood pressure, dizziness, high blood potassium, anemia, injury to the kidney, and increased liver enzymes in the blood.
Excerpted from Wikipedia’s “sparsentan” article, available under the CC BY-SA 4.0 licence.