Spiramide

Also known as AMI-193, R-5808

Spiramide (developmental code name AMI-193) is an experimental antipsychotic that acts as a selective 5-HT2A, 5-HT1A, and D2 receptor antagonist. It has negligible affinity for the 5-HT2C receptor. ==See also== Spirodecanone == References ==

Chemical data

Formula: C22H26FN3O2
Molecular weight: 383.5 g/mol
IUPAC name: 8-[3-(4-fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCOC4=CC=C(C=C4)F
InChIKey: FJUKDAZEABGEIH-UHFFFAOYSA-N
XLogP: 3.4
Polar surface area: 44.8 Å²
H-bond donors: 1
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: alkaloid
Has part: carbon
Mass: 383.200905

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canonical SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCOC4=CC=C(C=C4)F
chemical formula: C₂₂H₂₆FN₃O₂
World Health Organisation international non-proprietary name: spiramide
found in taxon: Spiraea japonica

Sources (2)

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