Also known as riboxamide, 2-(beta-D-ribofuranosyl)-4-thiazolecarboxamide, CI-909, TCAR, 2-beta-D-ribofuranosyl-4-thiazolecarboxamide
Tiazofurin is a drug which acts as an inhibitor of the enzyme IMP dehydrogenase. Tiazofurin and its analogues were under investigation for potential use in the treatment of cancer, though side effects such as pleuropericarditis and a flu-like syndrome precluded further development. They also show antiviral effects and may be reevaluated as potential options in the treatment of newly emerging viral diseases. ==Synthesis== [[File:Tiazofurin synthesis.svg|thumb|center|500px|ChemDrug Synthesis:]] The treatment of 1-O-Acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose [6974-32-9] (1) with trimethylsily
via Wikidata · CC0
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).