tiflorex

Tiflorex (TFX), formerly known as flutiorex, is a stimulant amphetamine that was under development as an appetite suppressant in the 1970s, but appears to have been abandoned. It is structurally related to fenfluramine and 4-MTA.

In the Vinony graph

Vinony's link graph records 1,487 inbound references to tiflorex, and connects out to phenethylamine, 2C-G and D-methamphetamine.

It is catalogued under topics including Abandoned drugs, Anorectics and Chemical pages without DrugBank identifier.

Vinony links it to 4 Wikipedia language editions.

Chemical data

Formula: C12H16F3NS
Molecular weight: 263.32 g/mol
IUPAC name: N-ethyl-1-[3-(trifluoromethylsulfanyl)phenyl]propan-2-amine
SMILES: CCNC(C)CC1=CC(=CC=C1)SC(F)(F)F
InChIKey: HNONSDNCRNUTCT-UHFFFAOYSA-N
XLogP: 4.3
Polar surface area: 37.3 Å²
H-bond donors: 1
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 263.096

Show 3 more facts

chemical formula: C₁₂H₁₆F₃NS
canonical SMILES: CCNC(C)CC1=CC(=CC=C1)SC(F)(F)F
Commons category: Tiflorex

Sources (2)

via Wikidata · CC0

~3 min read

Encyclopedic overview

5 sections

Contents

Pharmacology
Pharmacodynamics
Pharmacokinetics
Synthesis
References

{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449587989 | IUPAC_name = (RS)-N-ethyl-1-{3-[(trifluoromethyl)thio]phenyl}propan-2-amine | image = Tiflorex standardized.png | image_class = skin-invert-image | width = 260px | chirality = Racemic mixture | drug_name =

| tradename =

Excerpted from Wikipedia’s “tiflorex” article, available under the CC BY-SA 4.0 licence.