English
tolrestat
Sign in to saveAlso known as Alredase®, AY-27,773, AY-27773, N-((6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)thioxomethyl)-N-methylglycine, N-{[6-methoxy-5-(trifluoromethyl)-1-naphthyl]carbonothioyl}-N-methylglycine
Tolrestat (INN; AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications.
Research
238 papers- Tolrestat kinetics.Clinical pharmacology and therapeutics · 1984
- Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima.FEBS letters · 2020
- Tolrestat in the primary prevention of diabetic neuropathy.Diabetes care · 1995
- [Tolrestat in the therapy of diabetic peripheral neuropathy: is this drug really useful?].La Clinica terapeutica · 1995
- The efficacy of tolrestat in the treatment of diabetic peripheral neuropathy. A meta-analysis of individual patient data.Diabetes care · 1996
via PubMed
~2 min read
Encyclopedic overview
1 sectionsContents
- References
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