Structure via PubChem · Public domain (PubChem)
triamcinolone
Sign in to saveAlso known as fluoxiprednisolone, 9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione, 11beta,16alpha,17alpha,21-tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione, 9alpha-fluoro-16alpha-hydroxyprednisolone, 9alpha-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
Triamcinolone is a glucocorticoid used to treat certain skin diseases, allergies, and rheumatic disorders among others. It is also used to prevent worsening of asthma and chronic obstructive pulmonary disease (COPD). It can be taken in various ways including by mouth, injection into a muscle, and inhalation.
Key facts
- Drug.legal_AU
- S4
- Drug.CAS_number
- 124-94-7
- Drug.ATC_supplemental
- , , , , ,
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 470612980
- Drug.image
- Triamcinolone.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Triamcinolone ball-and-stick animation.gif
- Drug.width2
- 200
- Drug.tradename
- Kenalog, Nasacort, Adcortyl, others
- Drug.MedlinePlus
- a601122
- Drug.DailyMedID
- Triamcinolone
- Drug.pregnancy_AU
- A
- Drug.routes_of_administration
- By mouth, topical, intranasal, intramuscular, intra-articular, intra-synovial
- Drug.ATC_prefix
- A01
- Drug.ATC_suffix
- AC01
via Wikipedia infobox
Chemical data
- Formula
- C21H27FO6
- Molecular weight
- 394.4 g/mol
- IUPAC name
- (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O
- InChIKey
- GFNANZIMVAIWHM-OBYCQNJPSA-N
- XLogP
- 1.2
- Polar surface area
- 115 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
14,224 papers- Foveolar triamcinolone deposit.Journal francais d'ophtalmologie · 2022
- Triamcinolone: new and old indications.Expert opinion on pharmacotherapy · 2001
- Triamcinolone.Postgraduate medical journal · 1960
- Intramuscular triamcinolone.Journal of the American Academy of Dermatology · 2006
- [Triamcinolone].Orvosi hetilap · 1959
via PubMed
Wikidata facts
- Has part
- carbon
- Mass
- 394.179
- Has use
- medication
Show 9 more facts
- chemical formula
- C₂₁H₂₇FO₆
- Commons category
- Triamcinolone
- medical condition treated
- macular retinal edema
- canonical SMILES
- CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC43C)F)O
- isomeric SMILES
- C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O
- World Health Organisation international non-proprietary name
- triamcinolone
- defined daily dose
- 0.22
- subject has role
- glucocorticoid
- significant drug interaction
- hydrochlorothiazide
via Wikidata · CC0
~10 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Overdose
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- Society and culture
- References
- External links
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470612980 | image = Triamcinolone.svg | image_class = skin-invert-image | width = 200 | alt = | image2 = Triamcinolone ball-and-stick animation.gif | width2 = 200 | alt2 = | caption =
| pronounce = | tradename = Kenalog, Nasacort, Adcortyl, others | Drugs.com = | MedlinePlus = a601122 | DailyMedID = Triamcinolone | pregnancy_AU = A | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth, topical, intranasal, intramuscular, intra-articular, intra-synovial | class = | ATC_prefix = A01 | ATC_suffix = AC01 | ATC_supplemental = , , , , ,
Excerpted from Wikipedia’s “triamcinolone” article, available under the CC BY-SA 4.0 licence.