TRIM5α

Also known as RING-type E3 ubiquitin transferase TRIM5, ring finger protein 88, tripartite motif containing 5 transcript variant kappa, tripartite motif protein TRIM5, tripartite motif containing 5 transcript variant iota, TRIM5, tripartite motif-containing protein 5

Tripartite motif-containing protein 5 also known as RING finger protein 88 is a protein that in humans is encoded by the TRIM5 gene. The alpha isoform of this protein, TRIM5α, is a retrovirus restriction factor, which mediates a species-specific early block to retrovirus infection.