Valasiklovir

Also known as 256U87 HCl, valacyclovir hydrochloride (monohydrate), Valtrex®, Zelitrex®, L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine, Valaciclovirum, Valacyclovir

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In the Vinony graph

Within Vinony's link graph, Valasiklovir is referenced by 109 other articles, and connects out to antiviral drug, liver and kidney failure.

It is catalogued under topics including Amino acid derivatives, Anti-herpes virus drugs and Carboxylate esters.

Its subject is documented across 27 Wikipedia language editions.

Key facts

Drug.KEGG: D08664
Drug.Verifiedfields: changed
Drug.verifiedrevid: 470627698
Drug.image: Valaciclovir structure.svg
Drug.image_class: skin-invert-image
Drug.USAN: valacyclovir hydrochloride
Drug.tradename: Valtrex, Zelitrex, others
Drug.MedlinePlus: a695010
Drug.DailyMedID: Valacyclovir
Drug.pregnancy_AU: B3
Drug.routes_of_administration: By mouth
Drug.class: Antiviral
Drug.ATC_prefix: J05
Drug.ATC_suffix: AB11
Drug.legal_AU: S4
Drug.legal_UK: POM
Drug.legal_US: Rx-only
Drug.legal_status: Rx-only

via Wikipedia infobox

Chemical data

Formula: C13H20N6O4
Molecular weight: 324.34 g/mol
IUPAC name: 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
SMILES: CC(C)[C@@H](C(=O)OCCOCN1C=NC2=C1N=C(NC2=O)N)N
InChIKey: HDOVUKNUBWVHOX-QMMMGPOBSA-N
XLogP: -0.9
Polar surface area: 147 Å²
H-bond donors: 3
H-bond acceptors: 7
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1995
Admin. routes: oral
Indications: viral disease, chronic lymphocytic leukemia, cytomegalovirus infection, chronic hepatitis C virus infection

via ChEMBL · EBI