WFDC5
Sign in to saveAlso known as PRG5, WAP1, dJ211D12.5, WAP four-disulfide core domain 5
WAP four-disulfide core domain protein 5 is a protein that in humans is encoded by the WFDC5 gene.
In the Vinony graph
Within Vinony's link graph, WFDC5 is referenced by 2 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Its subject is documented across 5 Wikipedia language editions.
Gene data
WFDC5- Name
- WAP four-disulfide core domain 5
- Type
- protein-coding
- Position
- 45,109,452–45,115,217 (−)
- Aliases
- PRG5, WAP1, dJ211D12.5
- Ensembl
- ENSG00000175121
- RefSeq RNA
- NM_001395506.1, NM_145652.4, XM_011528601.2, XM_047439930.1, XM_054323072.1
- RefSeq protein
- NP_001382435.1, NP_663627.1, XP_011526903.1, XP_047295886.1, XP_054179047.1
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
WAP four-disulfide core domain 5
- Symbol
- WFDC5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:45,109,452-45,115,217
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- exact match
- identifiers.org/ncbigene/149708
- HomoloGene ID
- 17072
- found in taxon
- Homo sapiens
- genomic end
- 43743813
- genomic start
- 43738093
- chromosome
- human chromosome 20
- cytogenetic location
- 20q13.12
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
WAP four-disulfide core domain protein 5 is a protein that in humans is encoded by the WFDC5 gene.
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Excerpted from Wikipedia’s “WFDC5” article, available under the CC BY-SA 4.0 licence.