Genes on human chromosome 18

Vacuolar protein sorting-associated protein 4B is a protein that in humans is encoded by the VPS4B gene.

thumb|Secondary (A), Tertiary (B), and Quaternary (C) depictions of an aquaporin channel

class of enzymes

protein-coding gene in the species Homo sapiens

Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. Desmoglein-2 is highly expressed in epithelial cells and cardiomyocytes. Desmoglein-2 is localized to desmosome structures at regions of cell-cell contact and functions to structurally adhere adjacent cells together. In cardiac muscle, these regions are specialized regions known as intercalated discs. Mutations in desmoglein-2 have been associated with arrhythmogenic right ventricular cardiomyopathy and familial dilated cardiomyopathy.

Synaptotagmin-4 is a protein that in humans is encoded by the SYT4 gene.

Meprin A subunit beta is a protein that in humans is encoded by the MEP1B gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Dymeclin is a protein that in humans is encoded by the DYM gene.

protein-coding gene in the species Homo sapiens

Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression. It has been shown to play a role in chromatin modification through interaction with the histone H3K9 methyltransferase SETDB1. H3K9me3 is a repressive modification.

HAUS augmin-like complex subunit 1 is a protein that in humans is encoded by the HAUS1 gene.

Desmoglein-4 is a protein that in humans is encoded by the DSG4 gene.

GTP-binding protein Rit2 is a protein that in humans is encoded by the RIT2 gene.

Maspin (mammary serine protease inhibitor) is a protein that in humans is encoded by the SERPINB5 gene. This protein belongs to the serpin (serine protease inhibitor) superfamily. SERPINB5 was originally reported to function as a tumor suppressor gene in epithelial cells, suppressing the ability of cancer cells to invade and metastasize to other tissues. Furthermore, and consistent with an important biological function, Maspin knockout mice were reported to be non-viable, dying in early embryogenesis. However, a subsequent study using viral transduction as a method of gene transfer (rather tha

Microtubule-associated protein RP/EB family member 2 is a protein that in humans is encoded by the MAPRE2 gene.

Cilia and flagella associated protein 53 is a protein that in humans is encoded by the CFAP53 gene.

Sal-like protein 3, also known as zinc finger protein SALL3, is a protein that in humans in encoded by the SALL3 gene.

Centrosomal protein of 76 kDa, also known as CEP76, is a protein that in humans is encoded by the CEP76 gene.

Teashirt zinc finger homeobox 1 is a protein that in humans is encoded by the TSHZ1 gene.

Centrosomal protein of 192 kDa, also known as Cep192, is a protein that in humans is encoded by the CEP192 gene. It is the homolog of the C. elegans and D. melanogaster gene SPD-2.

Guanine nucleotide-binding protein G(olf) subunit alpha is a protein that in humans is encoded by the GNAL gene. Its main product is the heterotrimeric G-protein alpha subunit Golf-α, a member of the Gs alpha subunit family that is a key component of G protein-coupled receptor-regulated adenylyl cyclase signal transduction pathways in the olfactory system and the striatum in the brain. It also mediated D1 receptor signalling in the striatum and is hence involved in motor control.

Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene.

Protein SSXT is a protein that in humans is encoded by the SS18 gene.

Transmembrane protein 241 (aka C18orf45, hVVT) is a ubiquitous sugar transporter protein which in humans is encoded by the TMEM241 gene.

Lipoxygenase homology domains 1 is a protein in humans that is encoded by the LOXHD1 gene.

Desmocollin-1 is a protein that in humans is encoded by the DSC1 gene.

Divergent protein kinase domain 1C is a protein that in humans is encoded by the DIPK1C gene.

VAMP-Associated Protein A ( or Vesicle-Associated Membrane Protein-Associated Protein A) is a protein that in humans is encoded by the VAPA gene. Together with VAPB and VAPC it forms the VAP protein family. They are integral endoplasmic reticulum membrane proteins of the type II and are ubiquitous among eukaryotes.

Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP), is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post-synaptic density.

Oxysterol-binding protein-related protein 1 is a protein that in humans is encoded by the OSBPL1A gene.

Protein TRS85 homolog is a protein that in humans is encoded by the KIAA1012 gene.

Suppressor of cytokine signaling 6 is a protein that in humans is encoded by the SOCS6 gene.

Cell death activator CIDE-A is a protein that in humans is encoded by the CIDEA gene. Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids.

RNA polymerase II subunit A C-terminal domain phosphatase is an enzyme that in humans is encoded by the CTDP1 gene.

Myosin regulatory light chain 12A is a protein that in humans is encoded by the MYL12A gene.