Genes on human chromosome 1

Thyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene.

protein-coding gene in the species Homo sapiens

Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that in humans is encoded by the FDPS gene and catalyzes the transformation of dimethylallylpyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) into farnesylpyrophosphate (FPP).

TEX35 is a protein that in humans is encoded by the TEX35 gene.

Protein FAM20B is a protein that in humans is encoded by the FAM20B gene.

Fc receptor-like protein 5 is a protein that in humans is encoded by the FCRL5 gene. FCRL5 has also been designated as CD307 (cluster of differentiation 307).

p73 is a protein related to the p53 tumor protein. Because of its structural resemblance to p53, it has also been considered a tumor suppressor. It is involved in cell cycle regulation, and induction of apoptosis. Like p53, p73 is characterized by the presence of different isoforms of the protein. This is explained by splice variants, and an alternative promoter in the DNA sequence.

Low affinity immunoglobulin gamma Fc region receptor III-A is a protein that in humans is encoded by the FCGR3A gene. It is also known as CD16a as it is part of the cluster of differentiation cell surface molecules.

ATP-binding cassette, sub-family A (ABC1), member 4, also known as ABCA4 or ABCR, is a protein which in humans is encoded by the ABCA4 gene.

Acyl-coA acyltransferase-related enzyme 2 required for viability is a protein that in humans is encoded by the ARV1 gene. It is involved in lipid trafficking. ARV1 is ubiquitously expressed in higher eukaryotes, and in Saccharomyces cerevisiae yeast, is required for viability. Arv1-/- knockout mice display a phenotype with reduced white adipose and favorable blood lipid profiles on a chow diet. ARV1 is hypothesized to be involved in neurodevelopment, as a splice variant of ARV1 with a 40 amino acid truncation causes epileptic encephalopathy in infants.d Arv1-/- mice corroborate this observatio

Olfactory receptor 2G6 is a protein that in humans is encoded by the OR2G6 gene.

thumb | right | alt=Gene expression pattern of the NPHS2 gene. | Gene expression pattern of the NPHS2 gene. Podocin is a protein component of the filtration slits of podocytes. Glomerular capillary endothelial cells, the glomerular basement membrane and the filtration slits function as the filtration barrier of the kidney glomerulus. Mutations in the podocin gene NPHS2 can cause nephrotic syndrome, such as focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD). Symptoms may develop in the first few months of life (congenital nephrotic syndrome) or later in childhood.

Protein Wnt-3a is a protein that in humans is encoded by the WNT3A gene.

Cyclic AMP-dependent transcription factor ATF-3 is a protein that, in humans, is encoded by the ATF3 gene.

Borealin is a protein that in humans is encoded by the CDCA8 gene.

mammalian protein found in Homo sapiens

Insulin-like peptide 5 (INSL5) is a protein that in humans is encoded by the INSL5 gene.

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a cytoplasmatic protein encoded by gene PTPN22 and a member of PEST family of protein tyrosine phosphatases. This protein is also called "PEST-domain Enriched Phosphatase" ("PEP") or "Lymphoid phosphatase" ("LYP"). The name LYP is used strictly for the human protein encoded by PTPN22, but the name PEP is used only for its mouse homolog. However, both proteins have similar biological functions and show 70% identity in amino acid sequence. PTPN22 functions as a negative regulator of T cell receptor (TCR) signaling, which maintains hom

class of enzymes

protein-coding gene in the species Homo sapiens

Zinc finger protein 687 is a zinc finger protein that, in humans, is encoded by the ZNF687 gene.

protein family

Trafficking protein particle complex subunit 3 is a protein that in humans is encoded by the TRAPPC3 gene.

Disrupted in schizophrenia 1 is a protein that in humans is encoded by the DISC1 gene. In coordination with a wide array of interacting partners, DISC1 has been shown to participate in the regulation of cell proliferation, differentiation, migration, neuronal axon and dendrite outgrowth, mitochondrial transport, fission and/or fusion, and cell-to-cell adhesion. Several studies have shown that unregulated expression or altered protein structure of DISC1 may predispose individuals to the development of schizophrenia, clinical depression, bipolar disorder, and other psychiatric conditions. The ce

CREB regulated transcription coactivator 2, also known as CRTC2, is a protein which in humans is encoded by the CRTC2 gene.

Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.

Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene.

U4/U6 small nuclear ribonucleoprotein Prp3 is a protein that in humans is encoded by the PRPF3 gene.

Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene.

Integrator complex subunit 3 is a protein that in humans is encoded by the INTS3 gene.

PR domain zinc finger protein 2 is a protein that in humans is encoded by the PRDM2 gene.

Sodium/potassium-transporting ATPase subunit alpha-2 is a protein which in humans is encoded by the ATP1A2 gene.

Growth arrest and DNA-damage-inducible protein GADD45 alpha is a protein that in humans is encoded by the GADD45A gene.

Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene.

SLAM family member 7 is a protein that in humans is encoded by the SLAMF7 gene.

mammalian protein found in Homo sapiens

Probable ATP-dependent RNA helicase DDX59 is an enzyme that in humans is encoded by the DDX59 gene.

protein-coding gene in the species Homo sapiens

Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene.

Calpain-9 is a protein that in humans is encoded by the CAPN9 gene.

ETS domain-containing protein Elk-4 is a protein that in humans is encoded by the ELK4 gene.

Elongin A is a protein that in humans is encoded by the ELOA gene.

protein-coding gene in the species Homo sapiens

Transcriptional repressor p66-beta is a protein that in humans is encoded by the GATAD2B gene.

Calsyntenin-1 is a protein that in humans is encoded by the CLSTN1 gene.

Putative survival-related protein is a protein that in humans is encoded by the CASZ1 gene.

Exostosin-like 2 is a protein that in humans is encoded by the EXTL2 gene. EXTL2 Glycosyltransferase is required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. (https://www.phosphosite.org/overviewExecuteAction?id=5020882)

Type-1 angiotensin II receptor-associated protein is a protein that in humans is encoded by the AGTRAP gene.

Uncharacterized protein C1orf21, also known as Proliferation-Inducing Protein 13, is a protein that in humans is encoded by the C1orf21 gene. C1orf21 is an intracellular protein that flows between the nucleus and the cytoplasm in the cell. It has been linked with cell growth and reproduction and there has been strong links with various types of cancers. There are no paralogs for this gene, however, many conserved orthologs have been found in all invertebrates. C1orf21 has low to moderate level of expression in most tissues in humans, however, it has the most expression in the skin, lung and pr

Chromodomain-helicase-DNA-binding protein 5 is an enzyme that in humans is encoded by the CHD5 gene. It is a part of the CHD subfamily of ATP-dependent chromatin remodeling complexes.

thumb|327x327px|Cardiac sarcomere structure, featuring troponin T Cardiac muscle troponin T (cTnT) is a protein that in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration.

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.

Olfactory receptor 10K1 is a protein that in humans is encoded by the OR10K1 gene.

protein-coding gene in the species Homo sapiens

Nuclear ubiquitous casein and cyclin-dependent kinases substrate is a protein that in humans is encoded by the NUCKS1 gene.

Zinc finger protein 593 is a protein that in humans is encoded by the ZNF593 gene.

Regulator of G-protein signaling 2 is a protein that in humans is encoded by the RGS2 gene. It is part of a larger family of RGS proteins that control signalling through G-protein coupled receptors (GPCR).

Putative RNA-binding protein 15 is a protein that in humans is encoded by the RBM15 gene. It is an RNA-binding protein that acts as a key regulator of N6-Methyladenosine (m6A) methylation of RNAs

SPRY domain-containing SOCS box protein 1 is a protein that in humans is encoded by the SPSB1 gene.

Single-stranded DNA-binding protein 3 is a protein that in humans is encoded by the SSBP3 gene.