Structure via PubChem · Public domain (PubChem)
acenocoumarol
Sign in to saveAlso known as SIN350, Sinthrome®, Sintrom®, 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one, Acenokumarin, Acenocumarolo, 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one, 3-(alpha-p-Nitrophenyl-beta-acetylethyl)-4-hydroxycoumarin
Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is generic, so is marketed under many brand names worldwide.
Chemical data
- Formula
- C19H15NO6
- Molecular weight
- 353.3 g/mol
- IUPAC name
- 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]chromen-2-one
- SMILES
- CC(=O)CC(C1=CC=C(C=C1)[N+](=O)[O-])C2=C(C3=CC=CC=C3OC2=O)O
- InChIKey
- VABCILAOYCMVPS-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 109 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
1,876 papers- Acenocoumarol: A Review of Anticoagulant Efficacy and Safety.The Journal of the Association of Physicians of India · 2016
- Biomodification of acenocoumarol by bifidobacteria.FEMS microbiology letters · 2021
- Rosuvastatin-acenocoumarol interaction.Clinical therapeutics · 2005
- Hemoptysis Associated With Therapeutic Doses of Acenocoumarol.Archivos de bronconeumologia · 2019
- A Brief Review on Determination of Acenocoumarol in Biological and Pharmaceutical Specimens: Analytical Methodologies.Critical reviews in analytical chemistry · 2022
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 353.089937
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₉H₁₅NO₆
- significant drug interaction
- clarithromycin
- canonical SMILES
- CC(=O)CC(C1=CC=C(C=C1)[N+](=O)[O-])C2=C(C3=CC=CC=C3OC2=O)O
- World Health Organisation international non-proprietary name
- acenocoumarol
- Commons category
- Acenocoumarol
- defined daily dose
- 5
- subject has role
- anticoagulant
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is generic, so is marketed under many brand names worldwide.
== References ==
Excerpted from Wikipedia’s “acenocoumarol” article, available under the CC BY-SA 4.0 licence.