
thumb|250px|Adenosine diphosphate ribose|ADP-ribose ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. Improper ADP-ribosylation has been implicated in some forms of cancer. It is also the basis for the toxicity of bacterial compounds such as cholera toxin, diphtheria toxin, and others.
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二磷酸腺苷核糖基化(英語:ADP-ribosylation,ADP-核糖基化)是将额外的单个或多个二磷酸腺苷核糖(ADP核糖)基团添加到蛋白质的氨基酸残基上的轉譯后修饰过程。这一过程可逆,涉及许多细胞中的过程,包括细胞信号传送、DNA修復、基因表达调控和细胞凋亡。 异常的ADP-核糖基化已被证明和一些癌症相关。它也是來自细菌的毒素之致病机理,如、等。
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).