azosemide

Also known as 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazole, Diart, 2-chloro-5-(1H-tetrazol-5-yl)-N(4)-2-thenylsulfanilamide

Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim. As of 2015 it was available as a generic in some Asian countries.

Research

120 papers

Pharmacokinetics and pharmacodynamics of azosemide.Biopharmaceutics & drug disposition · 2003
Azosemide kinetics and dynamics.Clinical pharmacology and therapeutics · 1983
Pharmacokinetics and pharmacodynamics of azosemide after intravenous and oral administration to rats: absorption from various GI segments.Journal of pharmacokinetics and biopharmaceutics · 1996
The loop diuretic torasemide but not azosemide potentiates the anti-seizure and disease-modifying effects of midazolam in a rat model of birth asphyxia.Epilepsy & behavior : E&B · 2023
Circadian changes in the pharmacokinetics and pharmacodynamics of azosemide in rats.The Journal of pharmacy and pharmacology · 1998

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Wikidata facts

Mass: 370.007

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Commons category: Azosemide
chemical formula: C₁₂H₁₁ClN₆O₂S₂
canonical SMILES: C1=CSC(=C1)CNC2=CC(=C(C=C2C3=NNN=N3)S(=O)(=O)N)Cl
World Health Organisation international non-proprietary name: azosemide

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References

Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim. As of 2015 it was available as a generic in some Asian countries.

Azosemide has been found as an adulterant in ketamine. ==References==